Sodium and potassium movements in kidney cortex slices from newborn animals

Sodium Extrusion and Potassium Uptake in Guinea Pig Kidney Cortex Slices

Slices from the cortex corticis of the guinea pig kidney were immersed in a chilled solution without K and then reimmersed in warmer solutions. The Na and K concentrations and the membrane potential V(m) were then studied as a function of the Na and K concentrations of the reimmersion fluid. It was found that Na is extruded from the cells against a large electrochemical potential gradient. Q(10...

Relations between metabolism and the rate of turnover of sodium and potassium in guinea pig kidney-cortex slices.

It is now known that sodium and potassium ions exchange rapidly between cells and body fluids, and that the observed concentration gradients are not due to impermeability of the cell membrane (see reviews by Krogh, 1946; Ussing, 1949). It is also known that the production and maintenance of physiological concentration gradients of sodium and potassium in isolated kidney-cortex slices require re...

The effect of potassium on intracellular bicarbonate in slices of kidney cortex.

A release of renin from dog kidney cortex slices.

A release of renin from kidney cortex slices in vitro was first reported by the present authors (1). Recently, the renin release from kidney slices of rats, pretreated with de oxycorticosterone acetate, clipping of renal artery, bleeding or decapitation, was shown by Jong (2)' and BoCovic et al. (3). In their experiments, the fundamental process of renin release has not been made clear. In our ...

Sodium-Independent Uptake of Sugars by Brain-Cortex Slices

Experiments with the ventriculo-cisternal perfusion system in rabbits have shown that part of the extraction of [14C]glucose and 14C-labelled non-metabolizable glucose analogues from the perfusion system is Na+-dependent (Bradbury & Brerndsted, 1973). From this system in vivo sugars may be taken up by brain cells (neurones and glial cells) or they may pass into the circulating blood by crossing...